Benzocaine gels and liquids are sold OTC under different brand names such as Anbesol, Hurricaine, Orajel, Baby Orajel, Orabase, and store brands.  Benzocaine is also sold in other forms such as lozenges and spray solutions used to relieve pain from a variety of conditions, such as teething, canker sores, and irritations of the mouth and gums.

 Methemoglobinemia has been reported with all strengths of benzocaine gels and liquids with cases occurring mainly in children aged two years or younger who were treated with benzocaine gel for teething.  There have however, been cases reported in adults as well.

Some of the symptoms that may present with this condition are: pale, gray or blue colored skin, lips, and nail beds; shortness of breath; fatigue; confusion; headache; lightheadedness; and rapid heart rate.  These symptoms can appear within minutes to one or two hours after using benzocaine.  Symptoms may occur after using benzocaine for the first time, as well as after several uses.  These symptoms may be confused with other conditions therefore, if any of these symptoms present after using benzocaine, one should seek medical attention immediately.

 For parents who are seeking to comfort a child who is teething, some alternatives to benzocaine could be to give the child a teething ring that has been chilled in the refrigerator or to gently rub or massage the child’s gums with your finger. 

 For more information regarding this potentially life threatening condition, go to:

 http://www.fda.gov/Drugs/DrugSafety/ucm250024.htm